Similar genetic susceptibility in iatrogenic and sporadic Creutzfeldt-Jakob disease
نویسندگان
چکیده
منابع مشابه
Sporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease.
BACKGROUND The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons. OBJECTIVE To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging findings consistent with variant CJD (vCJD). RESULTS Results of a repeate...
متن کاملAutoantibodies in sporadic Creutzfeldt-Jakob disease.
IMPORTANCE The diagnosis of autoimmune and neurodegenerative conditions can be unclear. Treatments such as removing the associated tumor, if present, and immunosuppression can halt or often reverse the progression of autoimmune conditions, but there is no curative treatment for neurodegenerative conditions. The presence of autoantibodies can sometimes be misleading. This report illustrates pote...
متن کاملGenetic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease.
The ‘‘pulvinar sign’’ on MRI brain scan is defined as hyperintensity of the posterior thalamus relative to the signal intensity of the anterior putamen. In the appropriate clinical context, the pulvinar sign and hyperintensity in the dorsomedial thalamic nuclei (the hockey stick sign) are sensitive and specific features of variant Creutzfeldt– Jakob disease (vCJD). Variant CJD is an acquired fo...
متن کاملIatrogenic Creutzfeldt-Jakob Disease, Final Assessment
The era of iatrogenic Creutzfeldt-Jakob disease (CJD) has nearly closed; only occasional cases with exceptionally long incubation periods are still appearing. The principal sources of these outbreaks are contaminated growth hormone (226 cases) and dura mater grafts (228 cases) derived from human cadavers with undiagnosed CJD infections; a small number of additional cases are caused by neurosurg...
متن کاملIatrogenic transmission of Creutzfeldt-Jakob disease.
Creutzfeldt-Jakob disease is a rare progressive neurological disorder which is eventually fatal. Attention has recently been focused upon the iatrogenic transmission of this disease by four published reports of patients developing Creutzfeldt-Jakob disease associated with the administration of human growth hormone preparations originally prepared from human cadaver pituitaries. Characterized cl...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1994
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-75-1-23